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dc.contributor.advisorCastañeda Aphan, Benjamines_ES
dc.contributor.advisorSalcudean, Times_ES
dc.contributor.authorArroyo Barboza, Johnny Juniores_ES
dc.description.abstractBreast cancer is one of the greatest problems of national and international public health, whose incidence among women population shows an increasing trend. Nowadays there are several elastographic techniques, which seek to characterize the tissue, that is, to analyze the response produced by the application of a perturbation in the medium, to describe its mechanical properties. Among the modalities used are ultrasound, nuclear magnetic resonance and optical coherence tomography. On the other hand, among the types of disturbance used are low frequency mechanical waves, a uniform compression force or acoustic radiation force. In this thesis work, ultrasound was used due to its low economical cost in comparison to the other modalities. In addition, the type of perturbation selected was the external mechanical vibration, as it ensures the achievement of quantitative results, there is no risk of temperature rise in the analyzed area and allows the repeatability of the results obtained. Hence, two elastographic techniques were the axes of the present work: vibro-elastography and normal vibration holography. For the first, a calibrated phantom and a gelatin-based phantom were used, in order to characterize and validate the technique over a wide range of excitation frequencies. Posteriorly, 18 patients were analyzed prior biopsy exam, obtaining elastograms and contrasting them with the respective biopsy results. The results suggest that the technique is able to identify the presence of benign or malignant cancer, and the elasticity estimated agree with values reported in the literature. The second technique is proposed in the elastography field for the first time. Based on holography, its experimental scheme is established, and the mathematical expression for shear speed estimation is presented. Results from simulation and experiments performed on homogeneous and heterogeneous phantoms are presented, and the estimates are compared with previously obtained reference values. The results suggest that the estimates are close to the reference values for all media tested, and the technique must be studied in depth to revert artifacts formation.es_ES
dc.publisherPontificia Universidad Católica del Perúes_ES
dc.rightsAtribución-NoComercial-SinDerivadas 2.5 Perúes_ES
dc.sourcePontificia Universidad Católica del Perúes_ES
dc.sourceRepositorio de Tesis - PUCPes_ES
dc.subjectIngeniería de tejidoses_ES
dc.titleEvaluation of Elastographic techniques generated by means of external vibrationes_ES
dc.typeinfo:eu-repo/semantics/masterThesises_ESíster en Procesamiento de Señales e Imágenes Digitales.es_ESíaes_ES Universidad Católica del Perú. Escuela de Posgradoes_ES de Señales e Imágenes Digitales.es_ES

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